At Om Mushroom, we provide the best mushroom supplements for immune system support.
December 22, 2021

4 Best Mushroom Supplements for Immune System Support

With the season changing, it’s the perfect time to take care of your immune health. While we often turn to supplements to provide support once we’ve already fallen under the weather, natural supplements such as functional mushrooms can make a big impact in proactively supporting the immune system. Functional mushrooms contain powerful antioxidants, polysaccharides, and bioactive compounds that can provide immunomodulating effects that help to support healthy immune function. 

This page will provide a list of the four best mushroom supplements for immune system support offered at Om Mushroom to help keep your immune system in balance.

Functional Mushrooms That Support Immune Health 

Mushrooms have been used for centuries in Eastern cultures as nutritious foods and medicines to support general health and wellness. Of the many perceived benefits of functional mushrooms, immune support has been the star. 

Mushrooms contain beta-glucans and prebiotics; two powerful immune-supporting compounds. Beta-glucans help to activate and potentiate the immune system by activating a part of the immune system that enhances macrophages—the type of white blood cell that can detect and deconstruct harmful microorganisms and bacteria. Since beta-glucans occur naturally in the fungal cell walls of functional mushrooms, it makes many mushroom species the perfect natural supplement in supporting immune health. 

Mushrooms also act as prebiotics for your diet which help to support gut health—a primary component in maintaining good immune health since much of the immune system is housed in the gut. Additionally, mushrooms contain numerous bioactive compounds and impressive nutrients like protein, fiber, and potassium, all of which can help support general health and wellness as well as immune support.

Some functional mushrooms that support immune health include: 

  • Reishi: Reishi, also called the “elixir of life” and the “mushroom of immortality” contains many powerful bioactive compounds including beta-glucan polysaccharides and triterpenes. These help to promote the body’s defense against bacteria and viruses by heightening the body’s immune response. 
  • Chaga: The chaga mushroom is known to have some of the highest levels of antioxidants. Also called the king of mushrooms, chaga contains powerful nutrients like amino acids, B vitamins, and minerals which help to build the immune system. 
  • Turkey Tail: This powerful mushroom is packed with antioxidants including powerful flavonoids and more than 35 phenols. These help to support the immune system by stimulating the release of immune-supportive compounds. This mushroom is also known to support gut health which as we have discussed is crucial for immune health. 
  • Shiitake: A delicious culinary mushroom, lentinus edodes, or shiitake contains a high level of macronutrients and B vitamins and minerals that can easily be incorporated into daily recipes for optimal immune support. 
  • Maitake: Maitake contains beta-glucans and powerful bioactive compounds, but more importantly, maitake is also an adaptogenic mushroom. Adaptogens help support the body to better handle stress and its natural responses for immunity. Too much stress can cause many negative effects on the body. When incorporating a natural adaptogen into your diet, it can provide many positive benefits for your immune system and support for better health and wellness.
  • Lion’s Mane: This species contains many polysaccharides such as beta-glucans, prebiotic fibers, and digestive enzymes that support immune health and promote healthy gut flora.
  • Cordyceps: Cordyceps is known to support vitality, endurance, and stamina, but the polysaccharide content also supports gut health which helps to modulate the immune system. This species is also an adaptogenic mushroom, which can help the body to react appropriately to stress and help when challenged by infection.

While functional mushrooms have been used historically for many years for their support in immune health, modernly, mushrooms are cultivated indoors and often milled into powdered supplements for easier consumption. And when mushroom powder is consumed daily, it can provide tremendous benefits in building a strong immune system. 

Best Mushroom Supplements for Immune System Support

Since mushrooms can help to support the body’s immune system, adding a mushroom powder supplement can provide a convenient and natural way to add the nutritious superfood to your diet.

Om Mushroom has a variety of single- and multi-species mushroom powder blends that are designed to help support immune health. Each species is cultivated in a supervised, clean, and controlled environment at our indoor farm in Carlsbad, California. 

Here are our top four best mushroom supplements for immune system support. 

Om Mushroom Product

The Mushrooms Inside

The Benefits

How to Use

1. Immune Multi Boost Supplement with Vitamin C


This immune multi-boost includes 2,500mg blend of five functional mushrooms including, agaricus blazei, chaga, cordyceps, reishi, and turkey tail. 

In addition to the functional mushrooms, this supplement also contains 1,000mg of Vitamin C, high potency D3, and Zinc which can provide a great deal of immune support. 

Add one packet to 8oz of cold or hot water, stir well and enjoy.

2. Immune Blend Organic Mushroom Powder

Contains agaricus blazei, maitake, reishi, and turkey tail 

The powerful beta glucans, digestive enzymes, fiber, prebiotics, antioxidants, and other nutrients to keep your body battle ready.

Add one teaspoon (2 grams) daily to drinks, smoothies, or recipes. For optimal support, take 2 teaspoons (4 grams) per day. 

3. Immune Defense Mushroom Capsules

Contains agaricus blazei, maitake, reishi, and turkey tail

This supplement offers immune support from the powerful beta-glucans included, and includes Vitamin C for additional immune support.

Take three capsules per day with a glass of water. 

4. Immune+ Mushroom Drink Mix

Contains agaricus blazei, maitake, reishi, and turkey tail

This mix combines four species with Vitamin C, and 2 billion probiotics for optimal immune support. 

Combine 12oz of water with 1 tbs. of drink mix. Shake well and enjoy. This blend offers a fruity taste of superberry. 

Mushroom supplements are a natural and convenient way to help support your body’s immune system. Our top four best mushroom supplements for your immune system include an array of mushroom species to promote better wellness and optimal immune system support. 


These statements have not been evaluated by the Food and Drug Administration. Functional mushroom products are not intended to diagnose, treat, cure or prevent any disease.

Health & Immunity Superfoods

Adaptogenic mushroom products are easy to incorporate for everyday wellness. Om Mushrooms stand out from the rest because we develop, grow, and prepare all of our products on-site. And we use and love our products too!

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